Division of Biology and Medicine
Therapeutic Sciences Graduate Program

Nicolas Fawzi

Associate Professor of Molecular Biology, Cell Biology, and Biochemistry

Biography

We use nuclear magnetic resonance spectroscopy to see disordered protein structure, motions, and interactions with atomic resolution. We seek to understand how low complexity domains mediate phase separation contributing to membraneless organelle formation as well as some cancers, how disease mutations cause ALS and other neurodegenerative diseases, and how post-translational modifications alter interactions and may serve as a switch to prevent disease.