Therapeutic Sciences Graduate Program

My laboratory focuses on mechanisms of immune-mediate vascular remodeling by studying the macrophage-directed the biologic processes of arteriogenesis, atherosclerosis and atherosclerotic calcification, and pulmonary arterial hypertension. The overarching goal of the research in my lab is to define macrophage-dependent signaling mechanisms that modulate these processes in order to identify novel targets for the development of new inhibitory strategies that might one day be used in the clinic.  My laboratory has a number of active studies defining novel macrophage-dependent signaling mechanisms that modulate these processes, using a diverse array of techniques in molecular biology, immunobiology, small animal genetics, and vascular biology.